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Proven ingredients to help you Fight Stress!

Everyday Stress can be managed. Supplizen Advanced De-stress formula is a blend of scientific & natural ingredients that can help you fight stress. Our unique ingredients have been scientifically proven to reduce stress, calm you down and elevate your mood. Supplizen Advanced De-Stress Formula contains proven special ingredients like Ashwagandha, GABA, 5-HTP, Chamomile extract, St. Johns’ Wort and many more essential vitamins and minerals that will help you destress. Don’t miss to get on this routine for a better you today! 

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SCIENCE BEHIND INGREDIENTS

1. B Vitamins (Thiamine, Riboflavin, Niacin, B6, Folate, B12): Vitamin B supplementation is known to improve mood and energy levels and reduce the symptoms of stress. B Vitamins help lower the levels of Homocysteine (amino acid) which is associated with stress and stress related diseases.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/ 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290459/ 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316433/ 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337226/

https://pubmed.ncbi.nlm.nih.gov/18425703/   

 

2. Calcium: Stress hormone ‘Cortisol’ is released in blood stream when we feel stressed. This alters the homeostasis. To bring the pH back to normal, body releases Calcium from bones and teeth. Hence chronic stress may lead to weaker bones and make an individual prone to stress fractures. Supplementation with Calcium thus helps replenish the depleted calcium. Calcium also has a role in maintaining a healthy nervous system, it assists signal transfer between nerve endings. 

https://pubmed.ncbi.nlm.nih.gov/1786581/ 

https://pubmed.ncbi.nlm.nih.gov/16955721/ 

https://www.sciencedirect.com/science/article/abs/pii/S0161589001001080 

 

3. Magnesium

Magnesium is a regulator of neurotransmitters in brain, they are responsible for sending signals to brain and the body. Thus, by supporting normal brain function, Magnesium helps the brain fight symptoms of stress. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024559/ 

https://www.sciencedirect.com/science/article/pii/S0028390811003054?via%3Dihub 

 

4. Ashwagandha Root Extract

Ashwagandha is an apoptogenic herb that helps body cope with stress. It has been sued for thousands of years to relieve stress and improve concentration. It is known to control the mediators of stress like cortisol and reduces the activity of HPA axis, which is a regulator of stress response. It also assists in improving the sleep quality thus reducing stress.

https://pubmed.ncbi.nlm.nih.gov/32201301/ 

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6979308/ 

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6979308/ 

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6979308/ 

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6750292/ 

 

5. GABA

GABA is a natural anti-anxiety neurotransmitter produced by the brain. Thus it helps the brain relax. Low levels of GABA may lead to stress symptoms, insomnia, and mood swings. Studies conducted in workers in Japan have shown GABA to help reduce mental fatigue. Studies have also shown that GABA may have a potential anti-depressant effect.

https://www.jstage.jst.go.jp/article/jnsv/57/1/57_1_9/_article 

https://www.tandfonline.com/doi/abs/10.1080/09637480802558508 

https://www.sciencedirect.com/science/article/abs/pii/S002839081100373X?via%3Dihub 

 

6.Chamomile Flower Extract

Chamomile is one of the most ancient traditional herbs that has been used to treat several ailments ranging from hay fever, common cold, inflammations to sleep disorders. It has a calming effect on nerves which helps manage stress and promote a feeling of calm. Studies have shown Chamomile extract to exert anxiolytic properties. Studies have also shown its efficacy in helping individuals sleep faster. This effect is described as hypnotic effect of chamomile extract.

 

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC2995283/ 

https://pubmed.ncbi.nlm.nih.gov/19593179/ 

https://pubmed.ncbi.nlm.nih.gov/15863883/ 

https://pubmed.ncbi.nlm.nih.gov/10411210/ 

 

7. 5 HTP

5 HTP is an amino acid produced by the body which in turn helps in production of Serotonin. Low levels of Serotonin are associated with depression, anxiety, and sleep disorders. 5 HTP supplementation restores Serotonin levels and thus helps alleviate symptoms of stress. Studies have also shown 5-HTP supplementation to help reduce the frequency of migraines & headaches.

https://pubmed.ncbi.nlm.nih.gov/17984558/ 

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4471964/ 

https://pubmed.ncbi.nlm.nih.gov/3536521/ 

https://pubmed.ncbi.nlm.nih.gov/3308389/ 

 

8. St John’s Wort

St John’s Wort is a flowering plant. Its flower extract has been used for centuries to treat mild to moderate depression. This has been supported by several studies. 

https://www.cochrane.org/CD000448/DEPRESSN_st.-johns-wort-for-treating-depression

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5010734/ 

https://pubmed.ncbi.nlm.nih.gov/28064110/